We are seeking a highly motivated and organized individual to work on research projects in the Gastrointestinal Unit laboratory of Dr. Andrew T. Chan. Specifically, we are looking for someone to assist in our ongoing translational research efforts within our clinical trials related to the prevention of gastrointestinal cancers and aspirin chemoprevention. Our studies combine genomics, genetics, proteomics, and cell biology to study the underlying biological mechanisms of aspirin chemoprevention and identify biomarkers for utility in precision medicine.
PRINCIPAL DUTIES AND RESPONSIBILITIES
The selected candidate will work independently on experimental research projects directly supervised the principal investigator and post-doctoral fellows (80%) and will also spend about 20% of his/her effort on laboratory management duties, including purchasing and organizing supplies, supervising equipment maintenance, and preparing stock solutions. Candidates will be expected to think independently and troubleshoot experiments with collaborative guidance from colleagues. Opportunities may arise for independent research projects that align with the mission of the laboratory for a technician who is highly motivated and productive.
The technician will be expected to assist in a number of translational research approaches epithelial cell isolation by FACS, immune cell profiling using cell sorting/cytometry on human biopsy specimens, maintain in vitro organoid tissue culture systems, in vitro drug testing on organoid cultures, DNA/RNA extractions for next-generation sequencing. The Research Technician will be expected to work full time (40 hours/week) including occasional weekend work.
•Excellent verbal and written communication skills.
•Ability to manage time effectively.
•Ability to work independently and as a collaborative team member.
•Ability to maintain accurate records.
•Ability to maintain and execute complex experiments.
•Ability to organize, analyze, summarize, and present data.
•Experience and proficiency in at least two of the following techniques are required, but additional is preferred: flow cytometry/FACS, mammalian tissue culture, biospecimen (blood, stool, tissue, urine) handling, immunohistochemistry/fluorescence or next-generation sequencing.
•Experience with Freezerworks, REDCAP, and FlowJo are not necessary, but preferred
•B.S. degree or equivalent in Biology, Biochemistry, Immunology or related discipline required. (Research Technician I and II)
•Or Master's degree in Biology, Biochemistry, Immunology or related discipline or 2+ years post-baccalaureate professional laboratory experience (Research Technician II)
Two or more years of biomedical laboratory experience or equivalent training
Posting ID: 559420291Posted: 2020-06-03