(Sr.) Principal Scientist - Molecular Cell Biologist at Boston, MA

Job Title: (Sr.) Principal Scientist – Molecular Cell Biologist

Location: Boston, MA 02210 United States

Duration: 06 Months

Shift Time: 8:00 AM to 5:00 PM

Lunch: 1 Hour

Qualifications:

We are responsible for inventing, characterizing, and advancing novel genetic therapeutics for a myriad of clinical applications.

Our team works cross-functionally within our organization across multiple platform technologies and disease areas. This role may require up to 10% travel for conferences or training.

Job Requirements:

B.S. and/or M.S. in biology or a closely related field with 3+ years of relevant laboratory experience

Qualified applicants must be authorized to work in the United States on a full-time basis.

Additional Skills/Preferences:

Significant aseptic cell culture experience, including gene therapy (e.g. AAV or LNP) experiments

Experience isolating nucleic acids and proteins from tissues

Experience planning and implementing experiments independently

Experience in molecular endpoints, including, PCR, qPCR, ddPCR, and protein analysis (Simple Western Jess, ELISA, MSD, Octet)

Familiarity with primer design, sequencing preparation, and analysis

Mouse and NHP Tissue processing is a plus

Experience using automation in workflows is a plus (i.e., liquid handling)

Excellent problem-solving skills and ability to troubleshoot complex issues

Strong organization, communication, and collaboration skills

Responsibilities:

Job Responsibilities

Work with team members to drive forward new gene therapy programs

Perform cell culture and molecular biology experiments and establish new functional assays to measure gene therapy outcomes both in vitro and in vivo.

Establish and characterize novel assays for endpoint analysis to in vivo studies

Work cross functionally to deliver data to the project team within expected timelines.

Maintain detailed documentation of scientific work in an electronic notebook.