Cell Line Development Scientist

Description:

·       The Oncology research department at BR is recruiting a Senior Scientist with a strong background in cellular and molecular biology to join their Target Discovery and Biology group based in Cambridge, MA.

·       The successful candidate will carry out cutting-edge research in the areas of oncology in close collaboration with other leading research groups within BR.

·       The candidate will have the responsibility of generating high-quality data to support the identification and validation of new targets, with the goal of accelerating drug discovery.

·       The candidate will make use of a variety of molecular and cellular biology techniques to unravel the cellular mechanisms that regulate the function of the identified targets. Additionally, the candidate will assess new state-of-the-art technologies and explore their potential for enhancing our ability to identify targets and create more accurate complex-disease models.

·       The ideal candidate should possess a solid background in molecular and cellular biology, along with proficiency in some of the leading technologies in the field.

·       We seek a motivated and ambitious scientist wishing to continue a successful scientific career in a fast-paced drug discovery environment.

Major accountabilities include:

• Design, perform and interpret in vitro experiments under the leadership of the Lab Head
• Propose experimental alternatives, explore and introduce novel technologies and approaches.
• Analyze and effectively report data, as well as presenting the data in different team meetings
• Safe and effectively work with radionuclides
• Critical reading of the literature and ability to apply it to the project
• Closely work with multiple teams across expertise groups within Oncology
• Efficiently contribute to maintain a functional laboratory, technical equipment and tools

Minimum requirements:

• MSc or BSc or qualified Lab Technician (apprenticeship/vocational training) in cellular biology, molecular biology or another relevant discipline (no PhD)
• At least, 2-5 years of biomedical research.
• Proficiency and hands-on experience in applying a wide range of cellular and molecular biological methods (in particular: CRISPR, qRT-PCR, cloning, cell culture, cell viability/death assays, transient/stable cell line generation, immunoblotting, FACS) and softwares such as Microsoft Office, prism, spotfire
• Experience using basic bioinformatics tools to support experimental design, data analysis and interpretation is considered a plus
• Excellent presentation and communication skills in English (oral/written)
• Used to successfully work within a highly productive and fast-paced environment
• Highly collaborative and self-motivated team player, with critical scientific thinking
• Excellent organizational skills