Senior Scientist, Developability [Contract]
•Today
| Hours | Full-time, Part-time |
|---|---|
| Location | San Mateo, California |
About this job
Job Description
Job Description
Description
Key Responsibilities
Skills Knowledge and Expertise
The role: BigHat Biosciences is looking for a hands-on, bench-driven scientist to perform IND-enabling developability assessments on late stage drug candidates from our Milliner Platform for AI-designed therapeutics. This is a lab-based 12-month contract role, with the possibility but no guarantee of conversion to full-time position. You'll spend the majority of your time at the bench executing complex stability studies.
Key Responsibilities
- Lead, design, and execute in-use dose solution studies to assess drug compatibility with administration materials.
- Develop highly sensitive protein characterization methods (qSEC, RP-HPLC, CEX, particle counting, etc) for assessing drug quality and recovery.
- Support late-stage characterization, including formulation screening, stress testing, and peptide mapping, to rank and advance lead candidates.
- Drive developability assessments (purity, stability, tolerability, biophysical properties) across programs, with strong attention to data interpretation and organization.
- Communicate with and manage external CROs for testing and analytics.
- Interpret and communicate scientific findings, propose next steps, and broadcast clearly across the organization.
- Proactively identify and scope state-of-the-art analytical tools and developability technologies.
Skills Knowledge and Expertise
- PhD in Biochemistry or relevant discipline with 5+ year(s) of industry experience; exceptional non-PhD candidates with deep bench experience will be considered.
- Experience developing and optimizing sensitive analytical chromatography-based methods is a must.
- Strong background in biophysical and analytical characterization of antibodies and antibody fragments: SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS.
- Track record of translating complex data into clear results and recommended actions.
- Enthusiastic about learning and onboarding new technologies to expand capabilities and improve work quality, timelines, throughput or cost.
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Full-time Jobs Part-time Jobs Gig Jobs Posting ID: 1296958059 Posted: 2026-10-04 Job Title: Senior Scientist Developability Contract
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