Scientist II

Scientist II – In Vivo Research | Ridgefield, CT | 12-Month Contract

Sigma, Inc. is seeking an experienced Scientist II for a 12-month contract opportunity supporting onsite research in Ridgefield, Connecticut. This role is ideal for a scientist with hands-on in vivo rodent research, cardiometabolic/renal disease models, and pharmaceutical, biotechnology, or CRO experience.

Job Details

Job Title: Scientist II
Location: Ridgefield, CT
Duration: 12 Months
Work Arrangement: Onsite
Employment Type: Contract

Job Summary

The Scientist II will independently conduct routine in vivo studies and support the development and validation of rodent models for cardiometabolic and cardio-renal-metabolic research. The successful candidate will apply scientific principles to experimental design, rodent dosing, health monitoring, sample collection, data analysis, and interpretation of study results.

This position requires strong hands-on laboratory skills, scientific problem-solving ability, attention to data integrity, and the ability to work effectively within a collaborative drug discovery environment.

Key Responsibilities

• Independently initiate and complete routine in vivo rodent studies with minimal supervision.
• Interpret experimental results and recommend appropriate follow-up studies.
• Support development and validation of rodent models for cardiometabolic diseases.
• Perform routine rodent dosing using IV, IP, PO, SC, and IM routes.
• Conduct animal health monitoring and biological sample collection.
• Perform literature searches and apply information from published scientific protocols.
• Identify and implement new technologies and process improvements supporting research.
• Operate, maintain, and troubleshoot laboratory equipment.
• Contribute to study protocols, procedures, technical reports, and scientific documentation.
• Maintain a high level of data integrity, scientific rigor, and ethical standards.
• Communicate research findings effectively both verbally and in writing.
• Collaborate with cross-functional scientific teams.
• Participate in weekend/holiday rotations as required by the research team.

Required Qualifications

• Master's degree with 2–3 years of relevant experience, OR Bachelor's degree with 3+ years of relevant experience in a related scientific discipline.
• Pharmaceutical, biotechnology, or CRO experience is highly desirable.
• PhD candidates are not applicable for this position.
• Hands-on in vivo research experience using rodent models.
• Experience with routine rodent dosing routes including:
  • Intravenous (IV)
  • Intraperitoneal (IP)
  • Oral (PO)
  • Subcutaneous (SC)
  • Intramuscular (IM)
• Experience with animal health monitoring and sample collection.
• Experience working within IACUC governance and compliance requirements.
• Strong problem-solving skills and ability to learn new techniques and technologies quickly.
• Ability to work effectively in a highly collaborative research environment.

Preferred Qualifications

• Direct experience with rodent models of chronic kidney disease (CKD).
• Experience in cardiometabolic, cardio-renal, or metabolic disease research.
• Experience supporting drug discovery and development programs.
• Experience incorporating new technologies into preclinical research.
• Experience with Microsoft Excel and GraphPad Prism for data analysis.
• Strong scientific writing and technical reporting skills.